Spero Therapeutics is looking for an experienced, collaborative, enthusiastic partner responsible for ensuring the robust application of traditional and emerging statistical methodologies to support the development and execution of clinical development strategies that deliver medically differentiated therapies that provide meaningful improvement to patients. In this role, the individual will provide strategic statistical input to the design, execution, analysis, and reporting of data for clinical and nonclinical studies and regulatory submissions across all Spero programs. Working in a cross-functional manner, this individual will liaise with various internal groups (Clinical, Nonclinical, Microbiology, Regulatory Affairs, Pharmacovigilance, and Medical Affairs) and external partners, including vendors and CROs for the delivery of statistics and data programming needs.

The Senior Director, DMPK, Bioanalysis, and Clinical Pharmacology, will report to the SVP, Clinical Development, with assigned responsibility to provide support to the Project Team Leaders. This individual will provide strategic guidance for the Phase 1 development programs and with Clinical Operations and the Project Team Leaders will be accountable for delivering clinical studies to agreed timelines and budget. This individual will supervise other Clinical Pharmacology, DMPK, and/or Bioanalysis consultants to ensure timely delivery of studies and documents.